OASIS landing

OASIS, the Osteoarthritis Medical Community

Intended for healthcare professionals

Developed by Laboratoires Expanscience together with independent experts.

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Test your knowledge on Osteoarthritis

What is OA (OsteoArthritis)?

OARSI (Osteoarthritis Research Society International) defines osteoarthritis as a disorder that involves mobile joints characterized by cellular stress and degradation of the extracellular matrix initiated by micro and macro lesions that activate maladaptive repair responses that include the pro-inflammatory pathways of innate immunity.1

The disease first manifests itself as a molecular derangement (abnormal joint tissue metabolism), followed by anatomic and/or physiological derangements (characterized by cartilage degradation, bone remodeling, osteophyte formation, joint inflammation and loss of normal joint function), which can culminate in illness.1

To learn more about OA tune into our podcast channel “Let’s Talk OA”:

1. Kraus VB, Blanco FJ, Englund M, Karsdal MA, Lohmander LS. Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use. Osteoarthritis Cartilage. 2015;23(8):1233-1241.

OARSI's definition of Osteoarthritis

According to the Osteoarthritis Research Society International (OARSI), OA is described as a condition affecting movable joints, characterized by cellular stress and degradation of the extracellular matrix. This degradation is initiated by both micro and macroscopic lesions, triggering maladaptive repair responses, including pathways associated with innate immunity’s pro-inflammatory mechanisms. Initially, the disease presents itself as a molecular disturbance, known as abnormal joint tissue metabolism. This is followed by anatomical and/or physiological disturbances typically marked by the following characteristics: cartilage degradation, bone remodeling, osteophyte formation, joint inflammation, and loss of normal joint function.1

Entities like OARSI have made several efforts to bring health authorities to recognize OA as a ‘serious disease’, due to its incapacitating aspects, the high levels of pain patients can experience on a daily basis, and the economic burden it represents. 2

To continue to learn about OA, tune into our podcast channel “Let’s Talk OA”:

1. Kraus VB, Blanco FJ, Englund M, Karsdal MA, Lohmander LS. Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use. Osteoarthritis Cartilage. 2015;23(8):1233-1241.

2. ​OARSI White Paper- OA as a Serious Disease

Why OASIS?

Prof. Yves Henrotin

“As a health professional, I know the importance of continuous training and staying current in scientific and medical matters. I extend an invitation to all healthcare professionals to remain up-to-date with valuable content updates on osteoarthritis available in the OASIS training modules.”

Prof. Ali Mobasheri

“I highly recommend experts in the osteoarthritis field to visit the OASIS website by Laboratoires Expanscience, as it offers rich and educational content. Some of the snackable learning formats featured include videos and a podcast series (“Let’s Talk OA”), which are particularly insightf ul and on which I’ve been a recurring guest speaker.”

Dr. Monique Chalem

“I have actively participated in the development of content for the OASIS website, where you will find relevant information about OA. I invite you to visit it. We continue to work actively in the pursuit of the well-being of people with this condition, which represents the most prevalent osteoarticular disorder and a significant cause of disability.”

OASIS has been endorsed by +90% of HCPs, as it has provided them with handy tools for their clinical practice.*

*Results from the first anonymous external survey to OASIS registered HCPs conducted in January 2022.

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